Product name:
HA-DOTATATE (Acetate salt)
Precursor for radiometal-labelled HA-DOTATATE
High Affinity DOTATATE for imaging & therapy
Molecular Weight:
1561.5 [g/mol]
Molecular Formula:
C65H89IN14O19S2
*Delivery time: On stock
General Information
Product no.: | 50001 |
Product name: | HA-DOTATATE (Acetate salt) |
Synonyms: | High-affinity DOTATATE, DOTA-3-iodo-Tyr3-octreotate |
Sequence: | DOTA-dPhe-Cys-Tyr(3-Iodo)-dTrp-Lys-Thr-Cys-Thr |
Molecular weight: | 1561.5 [g/mol] |
Molecular formula: | C65H89IN14O19S2 |
CAS no.: | n.a. |
Product description
Labelling precursor for [68Ga] or [177Lu].
For use by qualified personnel only.
Quantity
Product no. 50001: 250 µg net peptide (lyophilisate, acetate salt)
Packaging
Clear tubular glass vials type I (borosilicate, 2 mL) with lyophilisation stoppers and closed with aluminium caps.
Storage and Stability
Storage at -20°C (± 5°C). Protect from light.
A temperature increase up to +25ºC (± 2ºC) over a period of 14 days does not affect the purity of the chemical precursor.
Certificates
Certificate of Analysis
Certificate of Compliance
TSE/BSE Statement on request
Manufactured in full compliance with current GMP requirements. Specifications according to Ph. Eur. 2902 “Chemical precursors for radiopharmaceutical preparations”.
Literature
[1] Schottelius M. et al. Twins in spirit – episode I: comparative preclinical evaluation of [(68)Ga]DOTATATE and [(68)Ga]HA-DOTATATE. EJNMMI Res, 2015, 5:22.
[2] Hartmann H. et al. Dosimetric measurements of (68)Ga-high affinity DOTATATE: twins in spirit – part III. Nuklearmedizin, 2014, 53(5):211-6.
[3] Brogsitter C. et al. Twins in spirit part IV – [ 177 Lu] high affinity DOTATATE. A promising new tracer for peptide receptor radiotherapy? Nuklearmedizin, 2017, 56(1):1-8.
[4] Braat AJ et al. Gastrointestinal stromal tumour detection with somatostatin receptor imaging, 68Ga-HA-DOTATATE PET-CT. Lancet Oncol., 2017, 18(3).