Product name:
PSMA-11 (TFA salt)
Precursor for radiometal-labelled PSMA-11
Targeting of the prostate-specific membrane antigen for imaging
Molecular weight:
947.0 [g/mol]
Molecular formula:
C44H62N6O17
*Delivery time: On request
General Information
| Product No.: | 50215 |
| Product name: | PSMA-11 (TFA salt) |
| Synonyms: | Gozetotide, PSMA-HBED, Glu-Urea-Lys(Ahx)-HBED-CC |
| Sequence: | HO-Glu-CO-Lys(Ahx-CC-HBED)-OH |
| Molecular weight: | 947.0 [g/mol] |
| Molecular formula: | C44H62N6O17 |
| CAS No.: | 1366302-52-4 |
Product Description
Enantiomerically pure, chemical precursor for radiopharmaceutical preparations with [68Ga].
For use by qualified personnel only.
Quantity
Product No. 50215: 50 µg net peptide
Packaging
Amber glass vials type I (borosilicate, 2 mL) with lyophilisation stoppers and closed with aluminium caps.
Storage and Stability
Storage at -20°C (± 5°C). Protect from light.
Short-term storage (<1 month) at higher temperatures (e.g. during transport) does not affect product quality)
Certificates
Certificate of Analysis
Certificate of Compliance
Manufactured in full compliance with current GMP requirements.
Literature
[1] Rodnick, M. E., et al., Synthesis of 68Ga-radiopharmaceuticals using both generator-derived and cyclotron-produced 68Ga as exemplified by [68Ga]Ga-PSMA-11 for prostate cancer PET imaging, Nature Protocols 2022, 17, 980-1003.
[2] Siebinga, H. et al., The Impact of Peptide Amount on Tumor Uptake to Assess PSMA Receptor Saturation on 68Ga-PSMA-11 PET/CT in Patients with Primary Prostate Cancer, J. Nucl. Med. 2023, 64(1), 63-68.
[3] olde Heuvel, J, et al., Day-to-day variability of [68Ga]Ga-PSMA-11 accumulation in primary prostate cancer: effects on tracer uptake and visual interpretation, EJNMMI 2020, 10, 132.
[4] Meijer, D. et al., Biochemical Persistence of Prostate-Specific Antigen After Robot-Assisted Laparoscopic Radical Prostatectomy: Tumor Localizations Using PSMA PET/CT Imaging, J. Nucl. Med. 2021, 62(7), 961-967.
