Product name:
PSMA I&S (TFA salt)
Precursor for 99mTc-labelled PSMA I&S
Prostate-specific membrane antigen for SPECT imaging & radioguided surgery
Molecular Weight:
1299.4 [g/mol]
Molecular Formula:
C59H82N10O21S
*Delivery time: On request
General Information
| Product no.: | 50118 |
| Product name: | PSMA I&S (TFA) / Mannitol |
| Synonyms: | Mas3-y-NaI-k(sub-KuE) |
| Sequence: | Suber-1-oyl-ε-(Mercaptoacetyl-dSer-dSert-dSer-dTyr-d2NaI-dLys-OH)-8-oyl-ε-(HO-Glu-CO-Lys-OH) |
| Molecular weight: | 1299.4 [g/mol] |
| Molecular formula: | C59H82N10O21S |
| CAS no.: | n.a. |
Product description
Labelling precursor for [99mTc]PSMA I&S.
For use by qualified personnel only.
Quantity
Product No. 50118: 40 µg net peptide (lyophilisate, (TFA)/4mg mannitol)
Packaging
Clear tubular glass vials type I (borosilicate, 2 mL) with lyophilisation stoppers and closed with aluminium caps.
Storage and Stability
Storage at – 20°C (± 5°C) and protected from light. Storage of product at ambient temperature (+25°C) is not recommended.
A temperature increase up to +25ºC should not exceed a period of 24 hours.
Certificates
Certificate of Analysis
Certificate of Compliance
TSE/BSE Statement on request
Manufactured in full compliance with current GMP requirements. Specifications according to Ph. Eur. 2902 “Chemical precursors for radiopharmaceutical preparations”.
Literature
[1] Robu S. et al. Preclinical Evaluation and First Patient Application of 99mTc-PSMA-I&S for SPECT Imaging and Radioguided Surgery in Prostate Cancer, J Nucl Med, 2017, 58, 235-242
[2] Maurer T. et al. 99mTechnetium-based PSMA-specific Membrane Antigen-radioguided Surgery in Recurrent Prostate Cancer. Eur Urol. 2018 Apr 3. pii: S0302-2838(18)30189-1
[3] Aalbersberg E. A. et al. Automated synthesis and quality control of [99mTc]Tc-PSMA for radioguided surgery (in a [68Ga]Ga-PSMA workflow). EJNMMI Radiopharmacy and Chemistry, 2020 (5),10
