Quality Control

SCINTOMICS SCI8100 HPLC System:

 

High-end performance and powerful features in combination with an exceptional cost/performance ratio.

  • Encapsulated optics design to protect the optical components from fine dust or harmful gases, providing high detection sensitivity and a very stable baseline.
  • Seya-Namioka monochromator and a new blazed holographic concave grating enhance light intensity, ensuring high sensitivity over the entire wavelength range.
  • Automatic compressibility compensation ensures highly precise flow rates.
  • Automatic seal rinsing for improved longevity.
  • Optional vacuum degasser for complete removal of dissolved gases and air bubbles.
  • Column compartment with Peltier elements for accurate temperature control (4°C up to 90°C) and high retention time reproducibility.
  • Integrated tray to safely house solvent bottles.

Pumps:

 

1.  SCI8112 Isocratic Pump


Parallel dual-plunger pump
Easily upgraded to SCI8110 Quaternary pump

 

2. SCI8110 Quaternary Pump


Operating principle: Parallel dual-plunger pump, Low-pressure Gradient
Number of Solvents: up to 4
Gradient formation: 4-channel mixing valve
Composition Precision: < 0.1 %
Composition Accuracy: < 0.5 %

 

3. SCI8111 Binary Pump


Operating principle: Double Parallel dual-plunger pump, High-pressure Gradient
Number of Solvents: 2

Detectors:

 

1. SCI8160 PDA Detector

 

Slit Bandwidth:            1.7 nm
No. of PDA channels:   1024
Pixel Resolution:          0.9 nm
Wavelength:                 190~950 nm


Analytical Cell Semi-prep. Cell
Path-length: 10 mm Path-length: 3 mm
Pressure: < 1,500 psi Pressure: < 1,500 psi
Volume: 13 µl Volume: 5 µl
Noise Level: < ± 2•10-5 AU (empty cell, 1 sec Rise Time, 254 nm)
Drift: < 2•10-4 AU/hr (baseline correction), 0.001AU/hr (room temp)
Wavelength accuracy: < 1 nm (HY-1 Holmium Oxide Filter)
GLP Compliance: Photometric Accuracy, Linearity, Noise Level, Drift
System Check

 

2. SCI8120 UV/Vis Detector


Wavelength Range: 190-900 nm
Data collection rate: up to 50Hz
Light Source: Deuterium & Tungsten Lamp
Noise level: < ±0.35•10-5 AU, 254 nm, dry cell
Drift: < 1•10-4 AU/hr
Bandwidth: 5 nm
Wavelength Accuracy: ±1 nm
Wavelength Precision: ±0.1 nm
Linearity: >99.5 % for 2.5 AU (acetone, 254 nm)
Path length: 10 mm (analytical cell), 3 mm (semi-prep cell)
Cell Volume: 10 µl (analytical cell), 5 µl (semi-prep cell)

 

3. SCI8170 Refractive Index Detector


RI Range: 1.00 ~ 1.75 RIU
Noise: ≦ 5•10-9 RIU (analytical), ≦ 10•10-8 RIU (semi-prep)
Flow cell vol: 9 µl (analytical), 7 µl (semi-prep)
Cell pressure: 6 kg/cm2 (5.8 bar, 84 psi)
RS232 Control.

Further Options:

 

1. SCI8101 Vacuum Degasser


Number of channel: 4 Channels
Maximum flow rate: 10 ml/min per channel, > 0…2.0 ml/min per channel for removal of 70 % gas from Methanol
Internal volume per channel: 925 µl
Materials in contact with solvent: Teflon and PEEK

 

2. SCI8131 Column Compartment


Temperature range: 4 °C (Cooling) – 90 °C
Temperature stability: ±0.05 °C
Temperature accuracy: ±0.5 °C
Temperature programs: 40 Steps
Column capacity: Analytical : max. 3 ea of 30 cm column (max. OD 18 mm)
Semi-prep : Max. 2 ea of 30 cm column
Heat-up time: 16 minutes from 4 °C to 80 °C
Cool-down time: 13 minutes from 80 °C to 4 °C
Column switching: max. two automatic 6-port valve (optional)

 

3. SCI8150 Autosampler


A high-throughput autosampler with state of the art injection technology, fast injection and wash cycles, and an optional Peltier chiller/heater for samples. Full or partial loop injection along with Pressure-Assisted-Sample-Aspiration (PASATM) is possible. The highly efficient needle and internal capillary wash virtually eliminates sample carry-over. Cycle time, including wash, is less than one minute. 96 standard 2 ml vials (32 mm x 12 mm) or well plates (96 or 384 capacity, deep or shallow) can be used.
Sample capacity: Analytical : 2 micro well plates according to SBS standards
Semi-prep : 24 vials of 10 ml (LSV)
Loop volume: 1 – 9999 µl programmable
Reproducibility: RSD ≦ 0.3 % for full loop injections
RSD ≦ 0.5 % for partial loopfill injections
RSD ≦ 1.0 % for µl pickup injections
Carry-over: < 0.05 %
RS232 Control
Cooling/Heating option: 4 °C ~ 40 °C

2019 by SCINTOMICS GmbH | Sitemap | Imprint | Data Protection