siFalin-TATE

Product name:
siFalin-TATE/ siTATE

Chemical precursor for radiopharmaceutical preparations with [18F]

Molecular Weight:
2160.9 [g/mol] (m.i.),
2162.5 [g/mol] (av.)

Molecular Formula:
C98H141N18O30S2SiF

 

*Delivery time: On stock

General Information

Product no.: 50139
Product name: siFAlin-TATE, siTATE
Sequence: SiFAlin-Aoa-Asn(AcNH-β-Glc)-Asp2-PEG-Tyr³-octreotate
Molecular weight: 2160.9 [g/mol] (m.i.), 2162.5 [g/mol] (av.)
Molecular formula: C98H141N18O30S2SiF
CAS no.:  n.a.

 

Product description

Chemical precursor with SiFA (silicone-fluoride acceptor) for radiopharmaceutical preparations with [18F] in high radiochemical yields. siTATE allows imaging of somatostatin receptors, e.g. for the identification of neuroendocrine tumors.
For use by qualified personnel only.
For research use only.

Quantity

Product no. 50139:   150nmol± 10% (TFA salt)

Packaging

Clear tubular glass vials type I (borosilicate, 2 mL) with lyophilisation stoppers and closed with aluminium caps.

Storage and Stability

Storage at -20°C (± 5°C), sealed, away from moisture and protected from light.

Certificates

Certificate of Quality

Literature

[1] Gower-Fry, L. et al. (2021) Recent Advances in the Clinical Translation of Silicon Fluoride Acceptor (SiFA) 18F-Radiopharmaceuticals, Pharmaceuticals 2021, 14, 701

[2] Lindner S. et al. (2020) Automated production of [18F]SiTATE on a Scintomics GRP™ platform for PET/CT imaging of neuroendocrine tumors, Nuclear Medicine and Biology, 2020, 88–89 (2020) 86–95

[3] Lindner S. et al. (2020) Radiosynthesis of [18F]SiFAlin-TATE for clinical neuroendocrine tumor positron emission tomography, Nature protocols, 2020, https://doi.org/10.1038/s41596-020-00407-y

[4] Ilhan H. et al. (2019) Biodistribution and first clinical results of 18F-SiFAlin-TATE PET a novel 18F-labeled somatostatin analog for imaging of neuroendocrine tumors, Eur. J. Nucl. Med. Mol. Imaging, 2019, 47, 870–880 (2020)