siPSMA-14 R&D

siPSMA-14 R&D Grade

The acronym “si” in [18F]siPSMA stands for silicone, and more precisely SiFA (silicone-fluoride acceptor).
Labelling of radiopharmaceuticals that comprise of such a SiFA group can be produced with isotopic exchange at room temperature.

siPSMA-14 (R&D)

General Information

Product/Article No: 50138
Product name: siPSMA-14
Sequence: L-Glu-urea-L-Glu{D-Orn[Suc-ε-D-Lys-D-Dap(SiFA)-D-Cit-γ-L-Glu-urea-L-Glu]}
Molecular Weight: 1472.6 g/mol (av.)
Molecular Formula:  C61H94N13O26SiF

Product description

Labelling of radiopharmaceuticals that comprise of such a SiFA group can be produced with isotopic exchange at room temperature.

For use by qualified personnel only.

For research use only.

Quantity

Product No. 50138: 150nmol; TFA-salt

Packaging

2 mL ISO clear type I tubular glass vials (2R borosilicate clear glass vials type I);

13mm crimp neck;

Lyophilisation stoppers;

Flip-off seal.

Storage and Stability

Storage at – 20°C (± 5 °C) sealed storage, away from moisture and protected from light.

Certificates

Certificate of Quality.

Literature

Loeffler J. et al. (2022) Blocking Studies to Evaluate Receptor-Specific Radioligand Binding in the CAM Model by PET and MR Imaging, Cancers, 2022, 14 (16), 3870

Loeffler, J. et al. (2021) Comparison of Quantification of Target-Specific Accumulation of [18F]F-siPSMA-14 in the HET-CAM Model and in Mice Using PETMRI, Cancers, 2021, 13 (16), 4007